Calbindins are three different calcium-binding proteins: calbindin, calretinin and S100G. They were originally described as vitamin D-dependent calcium-binding proteins in the intestine and kidney of chicks and mammals. They are now classified in different subfamilies as they differ in the number of Ca 2+ binding EF hands.

中间神经元表达多种钙结合蛋白（calbindin 和 calretinin），而运动神经元则表达同源框基因 HB9。 分泌神经递质的神经元可通过化学合成和分泌所需的以下酶/转运蛋白来区分：囊泡谷氨酸转运体 1/2 (VGLUT1/2)（谷氨酸能神经元）、谷氨酸脱羧酶 1/2 (GAD1/2)（γ-氨基丁酸能神经元）、醛脱氢酶 1 家族成员 A1 (ALDH1A1) 和酪氨酸羟化酶 (TH)（多巴胺能神经元）、色氨酸羟化酶（羟色胺能神经元）以及胆碱乙酰转移酶 (ChAT)（胆碱能神经元）。 除了神经元以外，成 …

Calbindin is a calcium-binding protein found in certain neurons of the central nervous system. Its main role is to regulate the levels of intracellular calcium, which is crucial for the survival of neurons. It is also influenced by steroid hormones, including adrenal corticosteroids.

鈣結合蛋白 （英語： Calbindin）是一種專門跟生物內的鈣 離子 結合的蛋白質，屬於 肌鈣蛋白C 超家族。 這種蛋白最初被稱為27-kD的蛋白，在的雞十二指腸內由 維生素D 引導產生。 在腦內，這種蛋白質的生成與維生素D衍生的荷爾蒙沒有關連。 鈣結合蛋白含有4個活動鈣結合 域，兩個已失去與鈣結合功能的修改域。 鈣結合蛋白主要作為 運輸蛋白 的功能。 在 人體 中，可在 腸道 、 腎臟 、 胰島細胞 及 腦 內找到。 鈣結合蛋白可以分為兩種： 鈣結合蛋白-D9k 存在於 哺乳類 …

Dec 24, 2024 · CALB1 (Calbindin 1) is a Protein Coding gene. Diseases associated with CALB1 include Blessig's Cysts and Temporal Lobe Epilepsy. Among its related pathways are Metabolism of proteins and RNA Polymerase I Promoter Opening. Gene Ontology (GO) annotations related to this gene include calcium ion binding and vitamin D binding.

钙结合蛋白 （英语： Calbindin）是一种专门跟生物内的钙 离子 结合的蛋白质，属于 肌钙蛋白C 超家族。 这种蛋白最初被称为27-kD的蛋白，在的鸡十二指肠内由 维生素D 引导产生。 在脑内，这种蛋白质的生成与维生素D衍生的荷尔蒙没有关连。 钙结合蛋白含有4个活动钙结合 域，两个已失去与钙结合功能的修改域。 钙结合蛋白主要作为 运输蛋白 的功能。 在 人体 中，可在 肠道 、 肾脏 、 胰岛细胞 及 脑 内找到。 钙结合蛋白可以分为两种： 钙结合蛋白-D9k 存在于 哺乳类 …

Calbindin (also called cholecalcin, or vitamin D-dependent calcium-binding protein) is a vitamin D-dependent protein that binds calcium with high affinity (the calcium-binding regions are homologous to those of the calmodulin family), constituting approximately 2% of duodenal mucosal cell protein (found only in high amounts in the duodenum) in ...

Calbindin, a 28kD protein with a Ca2+ binding domain, was discovered in peripheral tissues (e.g., intestine and kidney), but has emerged as an interesting molecular marker in brain. For now, ‘marker’ may be the best term, as the exact function (s) of calbindin remain unclear.

Calbindin 1 is a protein that in humans is encoded by the CALB1 gene. It belongs to the calbindin family of calcium-binding proteins, along with calretinin (CALB2). [5]

Calbindin-D 9k (CaBP-9k) is a cytosolic calcium-binding protein that is expressed in a variety of tissues, such as uterus, placenta, intestine, kidney, pituitary gland and bone. At present, the precise role (s) of CaBP-9k remains to be clarified.