The Lancet22h
Trends in thyroid cancer incidence and overdiagnosis in the USA
In this issue of The Lancet Diabetes & Endocrinology, Michelle M Chen and colleagues1 report their findings on trends in the incidence of thyroid cancer in the USA from 1975 to 2019. The authors show ...
The Lancet2d
Estimated worldwide variation and trends in incidence of lung cancer by histological subtype in 2022 and over time: a population-based study
Estimated geographical and temporal distribution of lung-cancer incidence varied across the four main subtypes worldwide. Our ...
The Lancet1d
Overcoming the challenges of overtreating and undertreating inflammatory bowel disease
Several therapeutic advances have been achieved over the past two decades for inflammatory bowel disease (IBD). The expanding ...
The Lancet1d
First phase 3 trial of GLP-1 receptor agonist for neurodegeneration
The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...
The Lancet2d
Applying the estimand framework to inflammatory bowel disease clinical trials
Since the first, seminal randomised controlled trial (RCT) in inflammatory bowel disease (IBD) in 1955,1 the central tenets for high-quality clinical trials have been recognised as robust and ...
The Lancet3d
AI for mammography: making double screen-reading history
Artificial intelligence (AI) for mammography is an early exemplar of the integration of AI systems into clinical pathways and ...
The Lancet5d
Chronic obstructive pulmonary disease: new therapies and old needs
Chronic obstructive pulmonary disease (COPD) is a manifestation of structural violence, the process through which societies ...
The Lancet2d
Early antiviral therapy in adults with moderate to highly viraemic chronic hepatitis B
Existing treatment criteria for chronic hepatitis B virus (HBV) infection are mainly based on data from observational studies, such as the REVEAL study from Taiwan, which was initiated in the early ...
The Lancet6d
Rising mpox trends in DR Congo: the neglected spread of an epidemic
The monkeypox virus is causing concurrent outbreaks of mpox in Africa, with more and more frequent exportations outside the ...
The Lancet6d
Hughes Stovin syndrome is not associated with pulmonary embolism – Authors' reply
We would like to thank Nikolas Ruffer and Martin Krusche for their considered Correspondence; their letter raised an important point regarding the nomenclature used in our case report. The authors ...
The Lancet5d
Marcel Proust (1871–1922): a historico-medical review of his fatal asthma
Looking for the name of Marcel Proust on search engines, it seems that the centenary of his death (1922) has gone unnoticed by medical doctors. Several essays on his illness have already been ...
The Lancet6d
The ceasefire is essential to restore Lebanon's vital health-care services
Lebanon's people and health-care system have yet again endured devastating attacks as the war on Gaza extended into Lebanon. Since October, 2023, Israeli attacks on Lebanon have resulted in more than ...