This research focuses on how the mTOR pathway influences key renal cells in DN progression, providing a comprehensive understanding of its role in kidney damage.

The study reveals that excessive activation of mTOR contributes to kidney injury by inhibiting autophagy, increasing oxidative stress, and promoting inflammation. It examines the impact of mTOR on ...

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Dusseldorf (HHU) have studied the temporal pattern of insulin action on protein kinases in human muscle cells ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...

The study reveals that excessive activation of mTOR contributes to kidney injury by inhibiting autophagy, increasing oxidative stress, and promoting inflammation. It examines the impact of mTOR on ...