For decades, scientists have focused on amyloid plaques—abnormal clumps of misfolded proteins that accumulate between neurons ...

The study reveals that excessive activation of mTOR contributes to kidney injury by inhibiting autophagy, increasing oxidative stress, and promoting inflammation. It examines the impact of mTOR on ...

This research focuses on how the mTOR pathway influences key renal cells in DN progression, providing a comprehensive understanding of its role in kidney damage.

Promising therapies for platinum-resistant ovarian cancer produced mixed results in separate trials. The AKT inhibitor ...

Single-cell analysis revealed the molecular triggers that drive stem cells to become cancerous, which may help inform ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).

Researchers from the German Diabetes Center (DDZ) and the Heinrich Heine University Dusseldorf (HHU) have studied the temporal pattern of insulin action on protein kinases in human muscle cells ...

Cassava's strong liquidity with $128.6 million in cash supports early-stage development, yet long-term funding needs may lead to shareholder dilution. Learn more on SAVA stock here.

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...