In a recently completed Phase I trial of healthy volunteers, the therapy was found to be well-tolerated and to engage’ WNT1-inducible signalling pathway protein 1 (WISP1) at all tested doses.

Sclerosteosis arises from mutations in the SOST gene, causing abnormally high bone mass and skeletal overgrowth, which can ...

A far-reaching study has cast doubt on statistical methods used to identify long-distance signaling networks in plants. The ...

Figure 1: Key signaling pathways and targeted factors in dysregulated BC. This figure illustrates the major signaling pathways and their intricate crosstalk in BC, focusing on the GPCR ...

This study fills a crucial gap in our understanding of blood cell formation from human pluripotent stem cells (hPSCs). Genome-wide comparisons of hPSC-derived blood progenitor cells with in vivo blood ...

The fatigue and lack of motivation that many cancer patients experience near the end of life have been seen as the ...

Immediate use for the newly developed assembloids could include studying neurodevelopmental disorders such as autism.