Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have ...
The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz receptor and LRP5/6 co-receptor.
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Novel therapeutic approaches targeting the Wnt pathway in hepatocellular carcinomaHepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates.
We know today that Wnt and a handful of other signalling systems (Notch, Hedgehog, TGFβ (transforming growth factor-β)–BMP (bone morphogenetic protein) and receptor tyrosine kinases ...
Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these animals develops along a central axis from their "head" to "tail." ...
Researchers developed a coordination nanomedicine (ZnDHT NM) that targets tumor cells and cancer stem-like cells, enhancing ...
A recent study published in the Journal of Clinical Investigation by researchers at Johns Hopkins University School of Medicine and collaborators identified HMGA1 as a key epigenetic regulator that ...
Researchers have discovered that a single molecule, Wnt3, coordinates a two-step process of cell polarity orientation that enables jellyfish embryos to develop around a central axis, shedding light on ...
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