Researchers developed a coordination nanomedicine (ZnDHT NM) that targets tumor cells and cancer stem-like cells, enhancing ...

Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors in the world, and its incidence and mortality have ...

IntroductionHepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates. It arises from ...

Wnt signalling refers to a network of proteins that controls ... In the second step, Wnt3 sets off a cascade of PCP ...

Aside from the canonical Hippo signaling cascade with the key components MST1/2 (mammalian ... such as the epidermal growth factor receptor (EGFR)/ErbB family, Notch, and Wnt signaling as well as cell ...

Clinical Applications of lncRNA and Wnt/β-Catenin Signaling in HCC Overall, we elaborated the critical role of lncRNAs and the Wnt/β-catenin cascade in HCC to seek more hopeful and practical clinical ...

Conclusion Targeting the FTO/m6A/GPNMB axis could significantly suppress tumour growth and metastasis, and enhance immune activation, highlighting the potential of targeting FTO signalling with ...

Tumor metastasis, recurrence, and therapeutic resistance are the main reasons for the failure of clinical cancer treatment. Studies have found that ...

When this blood sugar level increases after a meal, the body sets a signal cascade in motion in order to bring it back down. In people suffering from diabetes, this regulatory mechanism no longer ...