A scene from the hill bomb on Church Street on July 6, 2024.

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

The six-acre lake at the heart of Wallace State Park doesn’t announce itself with dramatic cliffs or thundering waterfalls. Instead, it sits there with quiet confidence, its surface rippling gently ...