New structural markers of memory storage uncovered by Scripps Research may pave the way for new treatments for memory loss.

Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

Their presence suggests a reservoir of potential connections that can be activated when needed, serving as "blank slates" for new memory formation. Our understanding evolved further when researchers ...

The researchers also found that neurons involved in memory formation were not preferentially ... nanoscale 3D reconstruction of neuronal synapses in the mouse hippocampus. To examine structural ...

Researchers have revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work sheds light on the fundamentally flexible nature of how ...

In neurons, CD2AP is essential for dendritic spine formation and stability, while in microglia, excessive CD2AP activity may promote pathological synapse pruning . Recent studies indicate that ...

The process also fought inflammation and oxidative stress while promoting synapse formation in the brain. In the report, Lipton stated: "We also took down other misfolded or aggregated proteins such ...