The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

A comprehensive Thought Leaders Invited Review in Brain Medicine highlights the crucial role of CD2-associated protein (CD2AP ...

Furthermore, we currently have little understanding of the functional states of synapses on a cell-assembly basis. What is the overall signaling impact of synaptic inputs at physically non ...

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...

An electrical impulse cannot directly cross the gap so a different mechanism has to be used. Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ...

A protein that impacts Alzheimer’s disease offers new opportunities for targeted treatments, although its cell-specific ...

T cells, move over. B cells are now reported, in a recent paper in Nature, to have their own immunological synapses with APCs. Only this time the antigen is whole and B cells don't keep it to ...

With these synchronized neuron cultures, the team observed their gradual maturity over 100 days by monitoring the development of synapses, cell length, and electrical properties. By using RNA ...

So, they obtained cochlear samples from adult mice that had normal hearing and were either exposed to psilocin or left untreated and labeled the synapses between cochlear hair cells and auditory ...

Over the course of their lives, humans and other animals typically learn to avoid situations and stimuli that are dangerous or are perceived as threatening. Past neuroscience studies have gathered ...