Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

Researchers have identified the mitochondrial calcium uniporter as a critical protein in the strengthening of synaptic ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

Researchers in the Galej Group at EMBL Grenoble have provided new insights into the structure of the minor spliceosome, an essential RNA-protein ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

A new imaging technique reveals ribosomes work together when translating mRNA, preventing slowdowns in protein production. This discovery challenges prior beliefs and could revolutionize our ...

The combined use of both low-speed and highspeed extracts strongly supports the view that BKC inhibits replicative DNA polymerases. To confirm this result, we have also used CETSA to monitor BKC ...

Using a spectrum of methods, the authors characterized the mechanisms of action of both drugs, providing convincing evidence that BKC targets DNA polymerases and IBC selectively inhibits CHK2. The ...

Yet due to technical limitations and the delicate nature of studying human brain tissue, scientists have lacked a complete picture of how GABA A receptors, and their 19 subunits, come together to ...