DNA hydrogels are biocompatible drug delivery systems for targeted therapeutic interventions. Conventional DNA hydrogels, formed with many DNA nanostructure units, lead to increased preparation costs ...

By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...

Innovative Takumi-shaped DNA hydrogels exhibit prolonged retention and drug release, showcasing their potential as ...

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various ...

The Kostenki 11 site, located near the Don River, just 300 kilometers from Moscow, is one of the most significant Upper ...

DNA has gained significant attention as a promising hydrogel material thanks to its customizable physicochemical properties, ...

Due to the helical structure of DNA, there is an angular deviation in ... Quantum chemical calculations were then conducted on selected nucleotide subsets, focusing on the nitrogen atom positions ...

Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted within ...

A second approach would be to use structure-based synthesis ... For example, Y-family DNA polymerases have enlarged nucleotide-binding sites relative to replicative DNA polymerases.

Thus, the base sequence and three-dimensional structure information of DNA molecules are encoded ... chemical calculations performed on specific nucleotide subsets. Principal axis directions ...