Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking ...

It basically put a stop sign, called a stop codon, toward the beginning of the KEAP1 gene. Stop codons generally signal where a gene ends, so having one at the start would "break" the gene.

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College ...

More information: Jiangle Liu et al, RNA codon expansion via programmable pseudouridine editing and decoding, Nature (2025). DOI: 10.1038/s41586-025-09165-x ...

More information: Jiangle Liu et al, RNA codon expansion via programmable pseudouridine editing and decoding, Nature (2025). DOI: 10.1038/s41586-025-09165-x Provided by Peking University ...