On day 1, GLP-1 was infused to stimulate endogenous insulin release and suppress endogenous glucagon. On days 2–5, pancreatic endocrine clamps were performed using somatostatin infusions of ...

Somatostatin (SST) is secreted by islet δ-cells and by extraislet neuroendocrine cells. SST receptors have been identified on α- and β-cells, and exogenous SST inhibits insulin and glucagon ...

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One hormone that could serve this function is somatostatin, which acts as a brake to prevent blood sugar from rising to normal levels. Blood glucose levels are mainly regulated by the opposing actions ...

beta cells secrete insulin, and alpha cells secrete glucagon. Scientists have identified three additional cell types in islets, including cells that secrete the hormones somatostatin, ghrelin ...

They are present in clusters of cells that produce other hormones involved in metabolism, such as glucagon, which increases ...

Somatostatin is secreted by specific cells of the pancreas, called delta cells. It is a master regulator of insulin and glucagon – another hormone that works hand-in-hand with insulin to maintai ...