Medical treatment of the disease is usually with somatostatin analogs. An open, prospective, single-center study by Maiza et al. examined the long term (≤18 years) antihormonal and antitumor ...

Treatment of nonfunctioning neuroendocrine tumors with somatostatin analogs has been controversial, given the low antitumor effects of these drugs. The PROMID study group now reports that ...

Matching adjusted indirect comparison (MAIC) of 177Lu-DOTATATE vs. sunitinib as first-line (1L) treatment for advanced grade 2 (G2) pancreatic neuroendocrine tumors (pNETs). This is an ASCO Meeting ...

Among these are dopamine agonists and somatostatin analogs. While one would hope that the ACTH modulators would reduce tumor volume (of particular concern in patients with pituitary macroadenomas ...

Researchers randomized patients with advanced neuroendocrine tumors 2:1 to receive either cabozantinib or placebo.

Glucagon is regulated by the inhibitory effects of somatostatin. Human somatostatin binds to all five SSTRs, while the drug analog octreotide only binds to SSTR 2. However, the researchers ...

The combination of chemotherapy and radioembolization appeared safe and effective in patients with well-differentiated, liver-dominant, grade 3 NETs.