Use of a sodium-glucose cotransporter 2, or SGLT2, inhibitor combined with calorie restriction resulted in greater rates of type 2 diabetes remission compared with calorie restriction alone, according ...

With studies showing potential for SGLT2 inhibitors in heart failure ... Others were concerned that there was uncertainty about the mechanism. Cost was also a concern raised by cautious ...

Welcome, ladies and gentlemen, to AstraZeneca's full-year and Q4 2024 results conference call for investors and analysts. Before I hand over to AstraZeneca, I'd like to read the safe harbor statement.

For example, by building on the success of Forxiga (dapagliflozin), the first SGLT2 inhibitor to demonstrate ... the use of the drug in novel dual mechanism combinations across five indications ...

No effect on cardiovascular death There was discussion at ESC whether Kerendia should be used in place of the SGLT2 inhibitors ... but that reflects its mechanism of action and hospitalisation ...

use of SGLT2 inhibitors (especially in combination with RAAS inhibitors) can break this “vicious cycle” and provide cardio–renal protection. Insulin resistance is a prevalent pathological mechanism ...

In lupus nephritis(LN), the researchers treated NZB/W lupus mice with a selective histone deacetylase 6 (HDAC6) inhibitor for 4 weeks and showed ... SGLT belongs to the SLC5 gene family. SGLT1 and ...

SGLT2 inhibitors confer greater risk reductions for major adverse cardiovascular events in older adults with type 2 diabetes ...

“Our data suggest SGLT2 inhibition as a safe strategy to prevent kidney stone recurrence in patients with kidney stones ,” Dr Fuster’s team concluded. Other study findings indicate the empagliflozin ...