Rivaroxaban belongs to a newer class of drugs known as direct oral anticoagulants. As its blood-thinning effects are more predictable than those of warfarin, patients taking rivaroxaban don't need ...

Half of renally-cleared rivaroxaban is cleared as unchanged drug and half as inactive metabolites. ‡Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole ...

CHICAGO, IL—Patients who develop thrombus in the left ventricle following myocardial infarction fare equally well when treated with rivaroxaban (Xarelto; Bayer/Janssen) as they do with warfarin, the ...