The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a ... of Syk tyrosine kinase binding to membrane immune receptors and ...

Eph receptor tyrosine kinases are involved in many cellular processes, including axon guidance, cell migration and angiogenesis. Like many other receptor tyrosine kinases, the Eph receptors are ...

DelveInsight’s, “Colorectal Cancer Pipeline Insight 2025” report provides comprehensive insights about 195+ companies and ...

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

RET, a transmembrane receptor tyrosine kinase ... with less potency against other protein tyrosine kinases. The drugs have shown similar potency against both wild-type and gatekeeper mutated ...

Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.