Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid ...

Bitter flavours act as nature’s warning signs, evolved over hundreds of millions of years to steer us away from potentially ...

The escalating global prevalence of obesity and type 2 diabetes mellitus (T2DM) underscores the urgent need for innovative ...

Here, we discover lysophospholipids as endogenous pannexin activators, using activity-guided fractionation of mouse tissue extracts combined with untargeted metabolomics and electrophysiology. We show ...

The molecular world of bitter compounds has so far only been partially explored. Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich in Freising and the ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

From fries to soda, these fast-food items hijack your brain's pleasure center and make you crave them nonstop.

A surprising link between the immune system and brain behavior is emerging, as new research reveals how a single immune ...

S cientists have discovered what could be one of the most bitter substances known to date. The potent chemical compound comes ...

In the search for better ways to treat diabetes, researchers at the University of Geneva have uncovered a promising new ...

People who suffer from the autoimmune disease myasthenia gravis experience muscle weakness that can affect any of the muscles ...