The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

Within cell membranes, ion channel receptors typically activate in response to electrical, chemical or other specific stimuli ...

In addition to regulation of subcellular location, ERBB receptors are also regulated in ways that affect their signaling activity. Ultimately, the maturation, dimerization, activation, time of ...

Silent synapses are dormant neural connections that hold untapped brain potential. Discover how ketamine, exercise, and other ...

Discover a study that investigated whether scheduled IV acetaminophen administration would offer longer-lasting relief for ...

Now, investigators at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have uncovered how heat causes a critical receptor protein within cells to unfold and relay ...