In the default model, the graph representing each individual enhancer can be arbitrarily complicated. To show how the ABC Score formula can arise from the default model, we need to impose the further ...

Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company committed to delivering a new class of RNA therapeutics called Antibody Oligonucleotide Conjugates (AOCs™), today announced ...

Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells, Cell (2019). Guanshi Wang, Jesse Hauver, Zachary Thomas, Seth A. Darst, Alexandros Pertsinidis.

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...

entirely extinct group of eukaryotes.” Maybe Prototaxites was a fun guy if you got to know him, but he just didn’t fit in with the fungi. Elizabeth Rayne is a creature who writes. Her work has ...

They use a laboratory procedure called Polymerase Chain Reaction (PCR) to make copies of a particular stretch of DNA (up to 5,000 base-pairs). Even if they have a very small amount of DNA to begin ...

People with strong political views about immigration can wield significant influence by crafting tweets laden with metaphors, shaping how others grasp this hotly contested issue. Researchers ...

Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR ... bacteria, archaea and eukaryotes with specialized ...

Credit: Figure drawn by prof. Jussi Toppari A new functionalized fluorosensor detects enteroviral RNA with high sensitivity in real time. It marks a major step in safer, more effective viral ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Targeting Tyrosyl-DNA phosphodiesterase 1 ...