Pope Francis experienced two respiratory episodes Monday caused by a buildup of mucus, another setback for the Catholic Church leader as he nears his third week of hospitalization. The Holy See Press Office said the breathing setbacks were created by a buildup of mucus in the pope’s lungs and a bronchial spasm (a sudden tightening of airway muscles making breathing difficult).

Pope Francis has been put back on mechanical ventilation after suffering ‘two episodes of acute respiratory failure’. The latest update on the pope’s health from The Vatican said he has undergone two bronchoscopies.

Pope Francis was to be hospitalized for bronchitis treatment and necessary diagnostic testing after his Friday audiences, the Vatican said.