B-cell maturation antigen, or BCMA, is selectively expressed when plasma cells differentiate. It is almost absent on memory and naive B cells. The maintenance of long-lived plasma cells involves ...

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of ...

Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Our biceps and our brain cells may have more in common than previously thought ... a protein known to be important in memory.

A plasma cell develops from an immune system ... and determined that their antibody repertoires matched those of memory B cells in the peripheral blood." Prior to the research by Prabhakaran ...

A team from Osaka University has developed scSPOT, a new technique that reveals how immune cells called Tregs simultaneously ...

BCMA is preferentially expressed on plasma cells and other mature B cells ... and still maintain populations of memory B cells and B cell progenitors that allow for a functioning humoral immune ...

The study involved simulations and experiments conducted by scientists at Lam Research, the University of Colorado Boulder and the U.S. Department of Energy's Princeton Plasma Physics Laboratory ...

The bone marrow microenvironment also provides survival niches for antibody-secreting plasma cells and memory T and B cells. These niches are primarily associated with bone marrow stromal cells ...