In a first, scientists have identified promising drug candidates that can permanently disable a key cancer protein once deemed untreatable—a discovery that could revolutionize cancer treatment.

Identifying crucial peptide sequences involved in IRF5–protein interactions is essential. The development of specific small-molecule inhibitors to disrupt these processes offers a promising strategy ...

Kaken Pharmaceutical will hand Alumis $40 million in the near term for the rights to develop a late-stage tyrosine kinase 2 (TYK2) inhibitor as a dermatology treatment in Japan. The drug in ...

Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China Clinical Research Unit, Changhai Hospital, Naval Medical University, Shanghai 200433, China ...

Their previous work identified reversible inhibitors of cJun, but this latest work builds on that by discovering peptides that bind selectively and irreversibly within cells, permanently blocking ...

Their previous work identified reversible inhibitors of cJun, but this latest work builds on that by discovering peptides that bind selectively and irreversibly within cells, permanently blocking ...

Their previous work identified reversible inhibitors of cJun, but this latest work builds on that by discovering peptides that bind selectively and irreversibly within cells, permanently blocking cJun ...

Their previous work identified reversible inhibitors of cJun, but this latest work builds on that by discovering peptides that bind selectively and irreversibly within cells, permanently blocking ...

Lip balms and chapsticks have always been skincare staples, but thanks to the rise of peptide lip balms, they've gone from basic hydration heroes to beauty must-haves. Hailey Beiber's launching of the ...

This article reviews the role of caspases implicated in diverse programmed cell death mechanisms in acute lung injury and the status of research on relevant inhibitors against essential target ...