Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of ...

Fast Company's annual list of the World's Most Innovative Companies spotlights organizations across various industries that are driving meaningful change through groundbreaking ideas and ...

HOUSE, PA — Johnson & Johnson (NYSE: JNJ) announced promising topline data from its Phase 2b ANTHEM-UC clinical trial evaluating icotrokinra (JNJ-2113) as a treatment for moderately to severely active ...

Icotrokinra met all primary endpoints in the studies, demonstrating significant skin clearance and clinical remission.

Protagonist Therapeutics (PTGX) announced topline results from ANTHEM-UC, a Phase 2b study of icotrokinra, the first investigational targeted ...

Fast track was first introduced by FDA to expedite development and review of drugs to treat serious conditions lacking any FDA-approved drug,” commented Gary S. Jacob, Ph.D., Chief Executive Officer ...

At its center are peptides, short chains of amino acids that serve as the building blocks of proteins but have distinct therapeutic properties of their own. These versatile compounds occupy a ...

Nearly half of patients with moderate-to-severe plaque psoriasis (PsO) treated with icotrokinra achieved completely clear skin (IGA 0) at Week 24 in Phase 3 ICONIC-LEAD studyTopline results from Phase ...

Topline results from Phase 3 ICONIC-ADVANCE 1&2�studies show icotrokinra achieved co-primary endpoints and showed superiority to deucravacitinib in moderate-to-severe plaque PsO ...

More than 1m votes were cast (pretty epic, NGL) and now we have our winners. Presenting your absolute faves from the world of beauty... Here, on the Cosmo UK beauty desk, there are very few things ...

T cells constantly survey the body for signs of infection or malignancy through the recognition of fragments of antigens (peptides) complexed to molecules of the major histocompatibility complex.