The role of Nrf2 in periodontal disease by regulating lipid peroxidation, inflammation and apoptosis
The Keap1-Nrf2 signaling pathway is the most important cellular antioxidant system, controlling the expression of various antioxidant enzymes. In this paper, the anti-oxidative, anti-apoptotic and ...
News Medical on MSN8d
How olive oil bioactives regulate genes linked to insulin resistanceOlive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...
Western blot analysis revealed that FMNT enhanced Nrf2 and its downstream antioxidant enzymes through mechanisms including the PI3K/Akt signal pathway and the Nrf2-Keap1 complex disruption. The ...
The present study suggested that EUG exerted protective effects on pancreatic β cells in T1DM by attenuating apoptosis and oxidative stress through the activation of the NRF2 signaling pathway.
School of Public Health, Jilin University, Changchun, Jilin, 130021, P. R. China ...
Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone ...
News Medical on MSN18h
Interferon pathway activation identified as key driver in OPLL pathogenesisOssification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...
A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...
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