Another component of specific granules is human cathelicidin (hCAP-18). hCAP-18 can exert antibacterial effects as well as induce chemotaxis of more neutrophils, T-cells and monocytes to the site ...

They are the most abundant white blood cell and comprise 50–70% of the population under normal conditions.3 Neutrophils have multi-lobed nuclei generally with 3–5 segments joined by thin strands, ...

Neutrophils, once considered simple foot soldiers of innate immunity, are now recognized as complex players in cancer.

Many of the downregulated genes encoded enzymes involved in degradation and bactericidal processes, within neutrophil granules, or genes that are expressed at high levels on non-lymphocyte white ...

In all cases, the patients form three types of antibodies: against the genetic substance DNA, against histones, and against proteins from the neutrophil granules.

Neutrophils, when they encounter signs of infection or inflammation, typically respond initially by releasing, via exocytosis, milder compounds within “gelatinase granules”—capsule-like ...

Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage. Nature Communications, 2017; 8 (1) DOI: 10.1038/s41467-017-00770-7 ...

Neutrophil extracellular trap (NET) formation—a process known as NETosis—is increased in systemic lupus erythematosus (SLE), particularly in a distinct subset of proinflammatory, low-density ...

Article Published: 20 May 2015 The neutrophil-recruiting chemokine GCP-2/CXCL6 is expressed in cystic fibrosis airways and retains its functional properties after binding to extracellular DNA S ...

We have investigated the dynamics of exocytosis in single human neutrophils. The increase of membrane area associated with granule fusion was followed by time-resolved patch-clamp capacitance ...

They are the most abundant white blood cell and comprise 50–70% of the population under normal conditions.3 Neutrophils have multi-lobed nuclei generally with 3–5 segments joined by thin strands, ...