Drug nephrotoxicity is a common healthcare problem in hospitalized patients and a major limitation during drug development. Multi-segmented kidney organoids derived from human pluripotent stem cells ...

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In sibling comparisons, there was no association seen between NSAID use and fetal nephrotoxicity. In singleton-born children, increased risks were seen for exposure during the second and third ...

Aim: Cisplatin is an effective chemotherapeutic drug, but the application in clinical is greatly limited by its nephrotoxicity. Necrostatin-1 (Nec-1), an inhibitor of RIP1 kinase, has been reported to ...