Introduction The kidneys are responsible for maintaining water, electrolyte, and acid-base homeostasis. They are effective at removing metabolic waste products, xenobiotics (drugs and toxins) and ...

Microphysiological systems (MPS) are powerful predictive tools for assessing drug-induced kidney injuries. Previous MPS have examined single regions of the nephron, but lack simultaneous filtration, ...

In conclusion, we have uncovered the presence of the olfactory OR/G olf /AC3 signaling system in the kidney and demonstrated its specific localization in the distal nephron. Our data suggest a use of ...

Letter Published: 09 November 2003 WNK4 regulates the balance between renal NaCl reabsorption and K + secretion Kristopher T Kahle, Frederick H Wilson, Qiang Leng, Maria D Lalioti, Anthony D O ...