2 carries MYD88. BCWM.2 also exhibited hallmark WM genetic aberrations ... 2 cells also showed remarkable sensitivity to the B-cell lymphoma 2 inhibitor venetoclax and the Janus kinase 2/Interleukin-1 ...

Newer-generation Bruton's tyrosine kinase (BTK) inhibitors have found a place in the management of follicular lymphoma, a malignancy where the first-generation drug ibrutinib (Imbruvica ...

Jazz Pharmaceuticals has agreed another pipeline-building deal, this time paying $10 million upfront for rights to a KRAS inhibitor programme from UK biotech Redx Pharma, continuing a move into ...

Bristol-Myers Squibb has won FDA approval for the first LAG-3 inhibitor drug ahead of its rivals in cancer immunotherapy, including Merck & Co. The US regulator cleared BMS' LAG-3 drug relatlimab ...

Angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) are recommended widely as first-line treatments for hypertension in patients with diabetic or nondiabetic ...

Tumor necrosis factor (TNF)-α inhibitors are associated with an increased risk of fungal infections, according to the findings of a systematic review published in Mycoses. Investigators explored ...

Compared with DPP-4 inhibitors, SGLT2 inhibitors and GLP-1RAs conferred lower risks for COPD exacerbation among patients with type 2 diabetes. Among patients with type 2 diabetes (T2D) and active ...

Angiotensin-converting enzyme (ACE) inhibitors are oral medications that lower blood pressure. They are used to treat a variety of heart-related conditions including high blood pressure, coronary ...

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6 th Avenue, Tucson, Arizona 85723-0001, USA; Ronnie.Fass{at}va.gov Patients with gastro-oesophageal reflux disease (GORD) who are not responding to proton pump inhibitors (PPIs) given once daily are ...

Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education and School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China ...

Departments of Pharmacology and Chemistry, Vanderbilt University School of Medicine, 2220 Pierce Avenue, Nashville, Tennessee 37232, United States ...