A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function. Abnormalities in mtDNA are linked to various diseases and are also implicated in ...

In a nutshell Scientists discovered that the herpes virus protein UL12.5 hijacks the body’s own immune pathways to trigger reactivation from dormancy, challenging what we thought we knew about how ...

Mitochondrial RNA polymerase (POLRMT) is an RNA polymerase that executes the transcription of the mtDNA. In comparison to the POLγA-related neurological diseases, a relatively less neuronal pathology ...

The mitochondria act as the energy factories of our cells, creating ATP that drives our bodily functions. Inefficiencies in mitochondrial function have been associated with a variety of health ...

Officinae Bio's AI-driven sequence optimization expands Maravai's family of brands, enabling rapid, cost-effective nucleic acid therapy development Venice, Italy-based Officinae Bio's proprietary ...

Get Instant Summarized Text (Gist) A computational tool named NuFold has been developed to model 3D RNA structures, potentially accelerating medical discoveries by decades. This tool addresses the ...

Selective reduction of OPA1 or MFN1 significantly rescued mitochondrial abnormalities, survival, and locomotor activity, whereas reduction of MFN2 had no effect. RNA sequencing of the pons/medulla ...

Interestingly, the tiny conduits provided a means to transport not only viral particles, but also RNA, proteins and mitochondria, a cell's main source of energy, from infected to neighboring cells.