If you receive Microsoft Excel cannot access the file, There are several possible reasons error message you can use the following suggestions to resolve the issue.

Repair Microsoft Excel. Try a third-party tool to repair the Excel file. 1] Run Excel in Safe mode and disable add-ins This issue turns out to be caused due to a problematic add-in installed in Excel.

When attempting to open a document that has triggered the use of the Protected View feature, like an Excel document, a message would pop up saying, "Microsoft Excel cannot open or save any more ...