After pathogen clearance, macrophages shift phenotype to promote wound repair ... Prior experiments examining integrin-mediated podosome formation in BMDMs plated on plastic have shown that integrins ...

Each podosome is composed of a central core of a dense F-actin ... their specific biological activity and function still needs further elucidation. After chemotaxis, macrophages attach to each other ...

Department of Physiology, State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences and School of Basic Medicine, ...

The researchers also discovered that when these cells, called macrophages, eat live bacteria it triggers an inflammation response. But when they eat dead bacteria it doesn't. "When phagocytic ...

This important study reveals that disrupting fatty acid metabolism in macrophages significantly restricts the growth of Mycobacterium tuberculosis, showing that impaired lipid processing triggers ...