In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

In a study published in Cell, a research team led by Prof. Li Hanjie from the Shenzhen Institutes of Advanced Technology ...

Objective: Macrophages are increasingly recognized as crucial therapeutic targets in the treatment of diverse pathological conditions. While considerable research has focused on macrophage-related ...

New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically relevant data. Induced pluripotent stem cells (iPSCs) have given scientists ...

Macrophages are involved in all stages of HS genesis through phenotypic changes. M1-type macrophages primarily function in the early inflammatory phase by secreting pro-inflammatory factors, while ...

“By harnessing their power, we can do a lot to benefit human health.” Reference: “Neonatal fungi promote lifelong metabolic health through macrophage-dependent β cell development” by Jennifer Hampton ...

CAMSAP2 is dynamically localized at the Golgi during the reorientation process in directional cell migration. (A) Immunofluorescence staining of HT1080 located at the foremost edge of the cell wound ...

The study 'Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages' led by Professor Dr Jan Rybniker, who heads the Division of Infectious Diseases at ...

More information: Alexander Simonis et al, Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages, Molecular Systems Biology (2025). DOI: 10.1038/s44320-025 ...

Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 lysine 27 acetylation (H3K27ac) at promoters of human monocyte-derived macrophages, suggesting epigenetic memory.

BOSTON, Mass., March 24, 2025 (GLOBE NEWSWIRE) -- Aura Biosciences, Inc. (NASDAQ: AURA), a clinical-stage biotechnology company developing precision therapies for solid tumors designed to preserve ...