In a study published in Cell, a research team led by Prof. Li Hanjie from the Shenzhen Institutes of Advanced Technology ...

Here we show that SARS-CoV-2 mRNA vaccination significantly establishes histone H3 lysine 27 acetylation (H3K27ac) at promoters of human monocyte-derived macrophages, suggesting epigenetic memory.

Future studies are needed to confirm our findings in additional patients and to elucidate the underlying molecular mechanisms. Our data further suggest exploration of the therapeutic potential of ...

Get Instant Summarized Text (Gist) Macrophages, part of the innate immune system, can exhibit a form of immune memory by adjusting their molecular signaling after an infection. This adaptation can ...

Using a quantitative multiplex immunofluorescence assay (mIF ... New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically relevant data.