Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

Olga Rivera Ballesteros from the Center for Infectious Medicine (CIM) at the Department of Medicine, Huddinge (MedH) is ...

Pancreatic cancer is one of the leading causes of cancer-related mortality, with pancreatic ductal adenocarcinoma (PDAC) ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

In vivo macrophage or T cell depletion and in vitro cell coculture ... immunosuppression status of the tumour microenvironment and activation of an antitumorous CD8 + T cell response. Conclusions In ...

1Guangdong Provincial Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, P. R. China.

A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain. Their findings were published in Cell.

“In previous studies, we observed alterations in both lymphocytes and macrophages [large white blood cells that often reside in adipose tissue and are part of the innate immune system, engulfing and ...

The same team of scientists also showed that KROS 101 increased the proliferation of helper and cytotoxic T cells (CD4+ and CD8+), while ... “Targeting M2 macrophage polarization: The anti ...