to find drugs that will stop ecDNA being maintained within cancer cells, although they have not made their strategy public yet. Dutta is also very hopeful that such drugs will help target currently ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

A review paper published last year in European Journal of Medicinal Chemistry characterized Myc as the “oncogene from ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

This was a mighty challenge. The cells kept dying. Paleontologist Kyoko Hagino of Kochi University tried for twelve years until she finally cracked it with a cousin of the original organism.

Tumor mutational burden (TMB) was calculated by dividing the count of all nonsilent mutations (including missense single-nucleotide polymorphisms/indels) by the total size of the Tempus ... of ...

Carcinoma is a type of cancer that starts in cells that make up the skin or the tissue lining organs, such as the liver or kidneys. Like other types of cancer, carcinomas are abnormal cells that ...

Lymphocytes are white blood cells that help the body fight infection and disease. The healthy range for an adult is between 1,000 and 4,800 lymphocytes per microliter (µL) of blood. Doctors will ...

This reduction in SMAD4 levels promotes cellular myelocytomatosis (C-MYC) transcription, which in turn enhances Cyclin D1 transcription, ultimately facilitating BCa cell proliferation. The findings ...