Cullinan Therapeutics rebranded from oncology to immunology+oncology, focusing on CD19 TCEs for autoimmune diseases. Check ...

In this Review, we discuss whether the immune response to cell death results in a measurable immune response (such as antitumour immune responses, delayed-type hypersensitivity, antibody responses ...

Explore how machine learning is transforming immunology—from epitope prediction to smarter vaccine design—plus key challenges ...

without deposits of complement macrophage antigens (MAC), and major histocompatibility (MHC) class I staining. SRP and -hydroxy-3-methyl-glutaryl-coenzymereductase (HMGCR) antibodies were negative.

Hence psoriasis and arthritis of many types are due to both susceptibility variants of the MHC as well as variants that alter T ... One report has shown that an antibody to IL-15, which could inhibit ...

Oncolytic adenovirus was engineered for the forced ectopic delivery of peptide-MHC ligand of T cell receptors (TCRs) to ...

Predictive biomarkers of immunotherapy response are critical for clinical practice. In this study, baseline plasma sCD27 was ...

To investigate the mechanisms, the researchers established MHC-mismatched and xenogeneic aGVHD mouse models, infusing stem cells at different times of the day. Results indicated that while the ...

The study, published in The Lancet Microbe, found the ability of Nef protein to reduce the marker molecule, called cell surface MHC-I, is linked to the speed at which the latent reservoir shrinks ...

Monoclonal antibodies (mAbs) are medications that target specific proteins to help reduce inflammation in people with severe asthma. The FDA has approved six mAbs for asthma treatment so far.