Physician's Weekly14d
Impact of PROC Variant C101F on Protein C Stability
The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I ...
eLife28d
Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice
Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
Frontiers10mon
African swine fever virus MGF505–6R attenuates type I interferon production by targeting STING for degradation
African swine fever (ASF) is an acute hemorrhagic and devastating infectious disease affecting domestic pigs and wild boars. It is caused by the African swine fever virus (ASFV), which is ...
Frontiers2y
Duck TRIM29 negatively regulates type I IFN production by targeting MAVS
The innate immune response is a host defense mechanism that induces type I interferon and proinflammatory cytokines. Tripartite motif (TRIM) family proteins have ...
eLife8y
APP modulates KCC2 expression and function in hippocampal GABAergic inhibition
Alzheimer’s disease is the most common form of dementia. One of the hallmarks of the disease is the formation of sticky protein clumps called amyloid plaques in the brain. These plaques are formed ...