This paper entailed state-of-the-art experimental procedures to explore the binding of the Y674-R685 loop of the SARS-CoV-2 S-protein to three nAChRs – namely the human α4β2 and α7 subtypes ...

Acetylcholine (Ach) is a neurotransmitter that functions in both the central and peripheral nervous systems. It is a non-monoamine subtype, meaning that it does not contain an amino group ...

The α7 nicotinic acetylcholine receptor is a pentameric ligand-gated ion channel that modulates neuronal excitability, largely by allowing Ca2+ permeation. Agonist binding promotes transition from a ...

The aim of this paper is to review the animal and human data to date, linking in utero smoke exposure to negative neurodevelopmental outcomes. It is known that nicotine from cigarette smoke exerts its ...