Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal cellular functions. The DNA blueprint is carefully read, transcribed, and ...

This valuable study shows that locomotion-related modulations in the mouse visual cortex are not uniform but primarily affect neurons in muscarinic receptor-negative patches, which receive projections ...

Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Molecular Reaction Dynamics, Center for Carbon Neutral Chemistry, Institute of Chemistry, Chinese Academy of Sciences, ...

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, ...

SGLT2 inhibitors are medications designed to help manage blood sugar in people living with type 2 diabetes. Learn more about the different types, as well as the benefits and side effects.

The purpose of this Review is to explore the neuroprotective mechanisms of endurance exercise and highlight the importance of CRF in promoting healthy brain ageing. Key findings show how CRF mediates ...

New non-covalent BTK inhibitors like nemtabrutinib are now in development to bypass these resistance mechanisms. Indeed, beyond BTK inhibitors, several TKIs are currently in development. Nemtabrutinib ...

Despite the previous findings, the mechanisms underlying the inhibitory roles of C1 and C2B, as well as their disinhibition to enhance synaptic transmission remain unclear, as does the modulation of ...

Wojciech Jurczak, MD, PhD, discusses the future of B-cell lymphoma therapy, with a focus on Bruton's tyrosine kinase inhibitors and degraders. Wojciech Jurczak, MD, PhD, head of the department of ...

alongside a mechanism for coordinated oversight involving three key agencies including the Ministry of Finance, the Ministry of Public Security and the State Bank of Vietnam. The information was ...