Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a ...

Nutrient intake stimulates the secretion of the gastrointestinal incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which exert glucose ...

In fact, the more we learn about biochemical pathways that this class of drug targets ... peptide 1(GLP-1), a hormone from a family of chemical messengers called the incretins, which Belgian ...

In fact, the more we learn about biochemical pathways that this class of drug ... from a family of chemical messengers called the incretins, which Belgian physiologist Jean LaBarre first purified ...

However, more evidence is needed to solidify these observations, including, when possible, trials comparing the effects of incretin-based drugs for obesity with calorie-reduced diets on both outcomes ...

Want to apply for Canada PR? The country is set to introduce four new permanent residency (PR) pathways in 2025, even as the government plans to reduce its PR targets from 485,000 to 465,000, ...

Hunger is an ancestral and evolutionary survival instinct; its importance is evident in the complex and redundant pathways involving ... endocrine and neurologic signaling that controls energy ...

The Department of Telecommunications has introduced a groundbreaking initiative allowing Jio, BSNL, and Airtel users to make calls using any available network when their SIM signal is lost. This is ...