Semaglutide mimics the action of the natural protein glucagon-like peptide 1(GLP-1), a hormone from a family of chemical messengers called the incretins ... in pancreatic beta cells, in the ...

“The main side effects that we see are predictable when you understand the mechanism of action of these drugs,” Coviello told Salon. We’ve learned GLP-1 receptors are found all over the place in the ...

A slight majority of the effect was from weight loss ... particularly the emerging evidence that preservation of beta-cell function is possible. Until we achieve this dream, the implementation ...

This increased demand ultimately leads to pancreatic beta cell depletion ... comparable with the effect of GLP-1RA treatment. The duodenal mucosa is home to incretin hormone-producing cells, such as L ...

Amyloid beta (Aβ) generally accumulates first in cognitively normal ... These include: the role of genetic risk factors for sporadic AD (such as APOE) in non-cell autonomous functions, the ...

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical ...

Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Taking prescribed beta blockers during hematopoietic stem cell transplantation may increase mortality risk due to suppression of signals from nerves that promote bone marrow regeneration, according to ...

Eli Lilly has invested heavily into obesity, dominating the landscape—alongside semaglutide maker Novo Nordisk—with its ...