A new study from Fujita Health University sheds light on how a brain-produced form of estrogen known as neuroestrogen plays a ...

Panelists discuss how testing for specific changes in cancer cells, like ESR1 mutations, can help guide treatment choices for patients with hormone receptor-positive metastatic breast cancer.

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

Phytoestrogen is naturally found in many plants. Dietitians explain the impact on cancer risk, menopause symptoms and who should avoid foods with plant estrogen.

During a live event, Megan Kruse, MD, discussed NCCN guidelines and key therapies for patients with HR-positive metastatic ...

Estrogen receptor alpha (ER), progesterone receptor ... LS specimens from 354 patients for expression of ER, PR, and AR by immunohistochemistry (IHC) using diagnostic-grade reagents and protocols.

Estrogen receptor-positive (ER+) breast cancer, which makes up around 70% of all breast cancer cases, often becomes resistant to current hormone therapies. Now, researchers have designed and ...

State Key Laboratory of Pollution Control and Resource Reuse, Institute for the Environment and Health, Nanjing University, Nanjing, Jiangsu 210023, PR China ...

Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard-Karls-Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany Tübingen Center for ...

Northwestern Medicine investigators have discovered previously unknown metabolic changes that may contribute to the development of estrogen receptor–negative (ERneg) breast cancer, according to ...

This review highlights the structural basis of ghrelin octanoylation, particularly emphasizing the mechanism by which the ghrelin receptor recognizes this acyl-modified hormone. Figure 1. Biosynthesis ...