TRIF acts as a scaffold to signalling components that feed into the IFN-regulatory factor 3 (IRF3) or nuclear factor-κB (NF-κB) pathways, resulting in the transcriptional activation of IFNβ.

Inflammatory gene expression, including TLR2, TNF-α, MHC, CRP, TLR4, IRF3, complement pathway, IL-6, IFN-y, CD14, IL-10, TGF-β are altered in SCZ, while TNF-α, TLR4, IL-6, CD14 and IL-1 are altered in ...

The RIG-I/MAVS signaling pathway is divided into two branches ... interferon regulatory factors IRF-3 and IRF-7, to phosph-IRF3 and phosph-IRF7, respectively. The phosphorylated factors translocate to ...

Both Samuel and David, as youths, fulfill God's will; David and Goliath (1 Sam. 17:26,34-37,47); David gains the heart of all (18:16); Saul's jealousy of David (18:9-11). And David said to Saul, Let ...

Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong 510055, China Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, ...