Women with psoriasis show shorter drug survival for biologics, including IL-17/23 inhibitors, due to lower satisfaction and ...

Tourmaline Bio's Pacibekitug shows promise in IL-6 targeting for autoimmune diseases. Learn about its potential and ongoing trials. Read why TRML is a hold.

Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your ...

I think combination therapy is coming; it’s just a question of which combinations,’ says Arthur Kavanaugh, MD.

Former Juventus Next Gen coach Lamberto Zauli denies that he’s been contacted by Inter Milan for their new Under-23 ...

The FDA has approved Tremfya (guselkumab) for the treatment of adults with moderately to severely active Crohn disease.

Department of Medicine, University of Toronto, Women's College Hospital, and co-authors have found biologics targeting ...

ATOPIC dermatitis (AD) is the most common chronic inflammatory skin condition, affecting up to 10% of adults and up to 20% of children globally. The clinical manifestations of AD are diverse, varying ...

Specifically, based on its mechanism, “IL-23 is viewed by some as the overarching master cytokine in the psoriasis pathway,” said Fernandez, clinical assistant professor in the Department of ...

Heppner's lab reported in Nature Medicine that blocking IL-12 and IL-23 significantly reduced Alzheimer's-related brain changes in mice. "But we couldn't unravel the underlying mechanism with ...

In 2012, Heppner's lab reported in Nature Medicine that blocking IL-12 and IL-23 significantly reduced ... depending on whether the IL-12 signaling pathway was present or absent.