Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

Moma Therapeutics Inc. has disclosed tricyclic derivatives acting as Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.

IDEAYA Biosciences, Inc.’s IDYA share price has surged by 10.70%, which has investors questioning if this is right time to sell.

MOMA Therapeutics, a clinical-stage biopharmaceutical company discovering and developing a new generation of precision ...

For the first time, researchers have filmed in real time the disassembly of DNA at the atomic scale. This strand separation ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights into viral replication mechanisms.

By binding uniquely to the helicase domain of WRN, IDE275 (GSK959) delivers potent and selective inhibition across MSI-H models," said Michael White, Ph.D., Chief Scientific Officer, IDEAYA ...

Using cutting edge cryo-electron microscopy, the team of scientists were able to visualise a helicase enzyme (nature's DNA unzipping machine) in the process of unwinding DNA. DNA helicases are ...

Using cryo-electron microscopy and deep learning to observe the helicase Simian Virus 40 Large Tumor Antigen interacting with DNA, the laboratories of KAUST Assistant Professor Alfredo De Biasio ...