As the old adage goes, “When it rains, it pours.” This is precisely the case for residents and businesses of the embattled Ditsobotla Local Municipality in the North West. Violent clashes have ...

According to a survey conducted by Intuit Credit Karma, 80% of Americans have seen a noticeable increase in the price of groceries in the last few years, especially after the pandemic. No matter ...

Mental health professionals no longer diagnose ADD. Instead, they diagnose one of three types of ADHD: inattentive, hyperactive-impulsive, or combined. Attention deficit hyperactivity disorder ...

On Valentine’s Day, Lewis Hamilton enters a sprawling studio space in northwest London and intently stares at the magnificent creature standing off in the distance. “Sh-t,” says Hamilton to ...

M2 interacts with the small ubiquitin-like LC3 protein through a cytoplasmic C-terminal LC3-interacting region (LIR). Here, we report that M2 is cleaved by caspases, abolishing the M2–LC3 interaction.

Sirt1 demonstrates deacetylation effects on PGC-1α, HMGB1, FOXOs, and p53. It hinders the activation of NLRP3 inflammasome and NF-κB while also engaging with AMPK. It regulates inflammatory response, ...

Imagine an AI system capable of guiding a robot to manipulate physical objects as effortlessly as it navigates software menus. Such seamless integration of digital and physical tasks has long been the ...

Erythroblasts possess unique characteristics as they undergo differentiation from hematopoietic stem cells. During terminal erythropoiesis, these cells incorporate large amounts of iron in order to ...

Further analysis revealed that hyperoside downregulates the expression of autophagy-related proteins LC3 and Beclin1, concurrently decreasing the accumulation of autophagosomes, thereby suggesting its ...

Pharmacy Unit, Veneto Institute of Oncology IOV-IRCSS, Padova 35128, Italy ...