Apoptosis is the most studied form of cell death in AH; however, the role of cellular senescence, another response to cellular injury, in AH is unknown. Here, we explore the mechanisms of ALD ...

This study aimed to explore the effect of physcion on ALF associated with HMGB1/NLRP3 pathways and gut microbiota. C57BL/6 mice were used to establish animal model of ALF, LX-2 cells were used to ...

1 Department of Critical Care Medicine, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, China 2 Department of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University ...

And totally different cells might share senescence features. Take p16 and p21, two proteins identified as drivers of cell senescence. Even if some cells highly express p16, whereas others highly ...