Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Coal worker’s ...
This manuscript reports fundamental discoveries on how necrotic cells contribute to organ regeneration through apoptotic signalling to produce cells with non-lethal apoptotic caspase activity that ...
New research from the Regulatory RNA and Chromatin lab at the Josep Carreras Institute sheds light on one of these alterations: autophagy malfunction. The inner life of a cell is highly dynamic ...
ADPN regulated HMGB1 expression and HMGB1-mediated inflammatory response and autophagy in macrophages via AdipoR2/c-Jun. Moreover, ADPN impeded HMGB1and IL6 secretion in hypoxic macrophages, ...
Antibodies against cleaved Caspase-3, HMGB1, phospho-FGFR, TNF-α and Caspase-9 were bought from Cell Signaling Technology (Beverly, MA, United States). TGF-β antibody was purchased from Abcam ...